Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...
Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...
The illustration shows DNA being folded into a loop by an SMC motor called cohesin (in purple/blue). The purple part of the motor (with a red/green label) is the protein subunit NIPBL, which acts as a ...
Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make ...