The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate ...

If the development of blood vessels in the placenta is impaired, fetal growth retardation may result. Scientists from the German Cancer Research Center (DKFZ) and the Mannheim Medical Faculty of ...

The genome is a fascinating place, consisting of complex loops of DNA that are transcribed into RNA, which is translated into protein. However, DNA expression is controlled by factors beyond the ...

Six epigenetic features define the new Epigenetic Hallmarks of Cancer, an add-on to the widely accepted Hallmarks of Cancer. Scientists concluded that malignant transformation requires some degree of ...

If the genome is the blueprint of life, epigenetics is the control system that determines when, where, and how genes are expressed. By revealing how chemical modifications to DNA and chromatin shape ...

Metabolic diseases such as obesity, fatty liver, and insulin resistance are rapidly increasing worldwide, but fundamental methods to regulate the process of fat formation remain limited. In particular ...

Dr. Huda Zoghbi, founding director of the Duncan Neurological Research Institute (Duncan NRI) at Texas Children's and ...

The world watched on in awe as teams successfully administered a personalized gene therapy to infant KJ Muldoon ("Baby KJ"). This extraordinary achievement reignited public and scientific excitement ...