Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...

Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected ...

Epigenetic modifications encompass heritable changes in gene expression that do not involve alterations to the underlying DNA sequence. In cancer biology, these changes include DNA methylation, ...

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...

Scheme showing the structure of cytosine, 5-methylcytosine, and 5-hydroxymethylcytosine. Adding a methyl group to the DNA base cytosine represses gene expression in mammalian cells. To remove the ...

Arthropod-borne viruses (arboviruses), such as dengue and Zika viruses, transmit widely across the globe, posing threats to human health and biosecurity. They spread through the bites of arthropod ...

Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...

DNA is often seen as the blueprint of life—carrying the code to govern the development and traits of an organism—but “there are things beyond the DNA sequence,” says Xiaoqi Feng, a plant geneticist at ...