Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter discovered a new property of the molecular motors that shape our chromosomes. While six years ago ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

The illustration shows DNA being folded into a loop by an SMC motor called cohesin (in purple/blue). The purple part of the motor (with a red/green label) is the protein subunit NIPBL, which acts as a ...

From the first unzip of the double helix to the final joining of DNA fragments, replication is a carefully coordinated process. Understanding it helps explain how life preserves its genetic code with ...

New work shows that physical folding of the genome to control genes located far away may have been a critical turning point for life on Earth. For evolutionary biologists, what most distinguishes the ...

Researchers at The University of Texas MD Anderson Cancer Center have identified a key enzyme—RNase H2—that helps ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that ...

Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...