Researchers developed SynTrogo, a molecular tool enabling targeted synapse removal via engineered neuron–astrocyte ...

For the first time, researchers have confirmed that selectively pruning certain synapses in the brain can paradoxically ...

A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant Pau (IR Sant Pau), has achieved what for decades had been an elusive goal: ...

Both presenilin-1 or the less-studied presenilin-2 can act as the catalytic subunit of γ-secretase, the enzyme responsible for churning out Aβ peptides. A new study, published November 29 in Nature ...

The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...