eLife

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...
eLife

Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

HIV-1 envelope glycoprotein (Env), a gp120–gp41 trimer, undergoes coordinated conformational changes that drive membrane fusion and allow immune evasion by transiently concealing ...
PC Magazine

I Ditched Password Generators and Made a Better One in Excel. Here's How

Because many password generators aren't as random as they seem, I built an improved one in Excel—and I'll show you exactly how you can, too. When the IBM PC was new, I served as the president of the ...
BMJ Open

Generative artificial intelligence-driven chatbots and medical misinformation: an accuracy, referencing and readability audit

Objectives Artificial intelligence (AI)-driven chatbots have been rapidly adopted across research, education, business, ...
Wired

machine learning

WIRED is obsessed with what comes next. Through rigorous investigations and game-changing reporting, we tell stories that don’t just reflect the moment—they help create it. When you look back in 10, ...