What is Tesofensine and how does it work? What it is: A triple monoamine reuptake inhibitor How it works: Increases three neurotransmitters: → Dopamine → Norepinephrine → Serotonin What these affect: → Appetite → Satiety → Motivation → Energy expenditure Where it works: Primarily on the hypothalamus, leading to appetite suppression and caloric restriction. Key difference from GLP-1s: Unlike GLP-1s, Tesofensine does NOT slow gastric emptying. Why this matters: This may be helpful for people who:
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What is Tesofensine and how does it work? What it is: A triple monoamine reuptake inhibitor How it works: Increases three neurotransmitters: → Dopamine → Norepinephrine → Serotonin What these affect: → Appetite → Satiety → Motivation → Energy expenditure Where it works: Primarily on the hypothalamus, leading to appetite suppression and caloric restriction. Key difference from GLP-1s: Unlike GLP-1s, Tesofensine does NOT slow gastric emptying. Why this matters: This may be helpful for people who:
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